Disordered Patterns in Clustered Protein Data Bank and in Eukaryotic and Bacterial Proteomes

We have constructed the clustered Protein Data Bank and obtained clusters of chains of different identity inside each cluster, http://bioinfo.protres.ru/st_pdb/. We have compiled the largest database of disordered patterns (141) from the clustered PDB where identity between chains inside of a cluster is larger or equal to 75% (version of 28 June 2010) by using simple rules of selection. The results of these analyses would help to further our understanding of the physicochemical and structural determinants of intrinsically disordered regions that serve as molecular recognition elements. We have analyzed the occurrence of the selected patterns in 97 eukaryotic and in 26 bacterial proteomes. The disordered patterns appear more often in eukaryotic than in bacterial proteomes. The matrix of correlation coefficients between numbers of proteins where a disordered pattern from the library of 141 disordered patterns appears at least once in 9 kingdoms of eukaryota and 5 phyla of bacteria have been calculated. As a rule, the correlation coefficients are higher inside of the considered kingdom than between them. The patterns with the frequent occurrence in proteomes have low complexity (PPPPP, GGGGG, EEEED, HHHH, KKKKK, SSTSS, QQQQQP), and the type of patterns vary across different proteomes, http://bioinfo.protres.ru/fp/search_new_pattern.html

On the possibility of refining by means of optical location some astronomical parameters of the system - Earth-Moon

Optical location of moon in Earth-Moon system using artificial light reflector, on lunar surfac

Chemical Stabilization Features Of Ladle Furnace Slag In Ferrous Metallurgy

Nowadays due to the application expansion of secondary steel processing methods, which provide high-degree metal desulfurization, a problem of the ladle furnace slag (or high-calcium refining slag) stabilization arose in the ferrous metallurgy. This slag cannot be stabilized because of its self-disintegrating properties. Keywords: ladle furnace slag, secondary alumina production wastes, slag stabilization, belite, mayenit

‘Vychegodsky’: a new potato cultivar for the Republic of Komi

Background. The presented information refers to the completed stage of the breeding process carried out at the Institute of Agrobiotechnologies (Syktyvkar) that led to the development of a new mid-early table potato variety – ‘Vychegodsky’. This cultivar was obtained from controlled crossing of cvs. Svitanok Kievsky × Amadeus. The new variety underwent a comprehensive assessment for the main agronomic traits and genetic screening for resistance to wart disease, nematode, and viruses X and Y.Materials and methods. In 2020, according to the results of production tests performed in 2017–2019, the description of the new cv. ‘Vychegodsky’ was finalized. The registered cv. ‘Nevsky’ was chosen as the reference. The study was conducted in the Institute’s experiment fields with a six-field crop rotation, which ensured high soil fertility without the use of mineral or organic fertilizers. The soil was soddy-podzolic. The planting scheme was 70 × 30 cm, at a depth of 8–10 cm, over the experimental plot area of 52.5 m2  (250 tubers), with four replications.Results. The mid-early cultivar ‘Vychegodsky’ is described as follows: the plant is erect, 50–65 cm in height; tubers are roundish-oval, with yellow skin color and light yellow flesh. The studies have shown that in its agronomic traits in the Republic of Komi cv. ‘Vychegodsky’ exceeds the reference cv. ‘Nevsky’. Its yield is 34.3 t/ha, and its marketable tuber weight 55.1 g; it contains 15.7% of starch, 24.1% of dry matter, and 11.2 mg% of vitamin C. The cultivar demonstrates high field resistance to major potato diseases, and genetically determined resistance to wart disease and golden potato nematode.Conclusion. Thus, a new potato cultivar has been released and included into the State Register of Selection Achievements (National List of the Russian Federation)

Practical analytical solutions for benchmarking of 2-D and 3-D geodynamic Stokes problems with variable viscosity

Geodynamic modeling is often related with challenging computations involving solution of the Stokes and continuity equations under the condition of highly variable viscosity. Based on a new analytical approach we have developed particular analytical solutions for 2-D and 3-D incompressible Stokes flows with both linearly and exponentially variable viscosity. We demonstrate how these particular solutions can be converted into 2-D and 3-D test problems suitable for benchmarking numerical codes aimed at modeling various mantle convection and lithospheric dynamics problems. The Main advantage of this new generalized approach is that a large variety of benchmark solutions can be generated, including relatively complex cases with open model boundaries, non-vertical gravity and variable gradients of the viscosity and density fields, which are not parallel to the Cartesian axes. Examples of respective 2-D and 3-D MatLab codes are provided with this paper

Effect of Structure and Texture on Failure of Pipe Steel Sheets produced by TMCP

The method of orientation microscopy (EBSD) is used to study the structure and texture of low-carbon, low-alloy pipe steel sheets processed by controlled thermomechanical processing (TMCP). The temperatures of isothermal hot rolling varied. Samples cut from sheets showed a different fracture tendency during mechanical testing. The formation of cleavages (secondary cracks) during failure of steel is related to the presence of ferrite grains with orientation {001} <110> extended in the hot rolling direction. The formation of grains is a consequence of the isothermal hot rolling below the temperature

Безотходная переработка ковшевого и электропечного шлака

The actual problem of mineral resources depletion in ferrous metallurgy can be effectively solved by complex reuse of technogenic waste. That waste is mostly presented by EAF (electric arc furnace) slag and LF (ladle furnace) slag. These two kinds of slag have no complex full utilization. The residues of slag are going to the dump and then the slag dump locations pollute the environment. However, the residues of EAF and LF slag can be transformed into the valuable industrial product by interaction of the slag components. This work presents the research for joint wasteless processing of EAF and LF slag with production of Portland clinker and cast iron. The article describes disadvantages of known methods of each slag processing; the paper also shows the significance of LF slag utilization. Design and calculations of the research are presented as well as its experiment methodology. The final results show five chemical compositions for the mixtures, which allow the complex processing of this slag without any waste left. Such processing provides the production of cast iron and Portland clinker both meeting requirements of normative documents. The paper also describes the results of viscosity measurements of slag compositions, the obtained slag phases, and presents the final temperature conditions. The work also considers the results of industrial tests for the developed processing technology and a complete technological chain involving the use of tilt rotary furnaces. © 2021 National University of Science and Technology MISIS. All rights reserved

OPTIMIZATION OF METHODS FOR DIAGNOSTICS OF PATIENTS WITH TOXIC AND CIRRHOTIC LIVER LESIONS

Chronic liver disease is a serious problem for public health service. As a result of increasing alcoholization of population, drug addiction, number of patients with parenteral hepatitis (B, C, D) the conditions for significant increase of number of patients with hepatocirrhosis appear. The aim. of our study was to determine the most optima! methods of diagnostics of patients with toxic and cirrhotic lesions of liver. The object of the research was 67 patients treated, in Irkutsk Municipal Clinical Hospital N 1 during 2007—2011 years with liver cirrhosis. All the patients had. diagnostic laparoscopy with determination. of the level of cytokines, albumins and. gamma-globulins with further clinicomorphological and. statistical analysis of the results. It was revealed that complex use of instrumental and. laboratory methods allows to diagnose liver cirrhosis at the early stage of its progress very precisely.